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DTSTART;TZID=Europe/London:20260908T133000
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CREATED:20250922T143543Z
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UID:10000129-1788874200-1789489800@skillsacademy.newcastle-hospitals.nhs.uk
SUMMARY:Targeted treatments and immunotherapy for Lung Cancer - September 2026
DESCRIPTION:Delivered over two afternoon sessions\, Dr Elaine Vickers – a leading independent educator on the science of new cancer treatments – will guide you through many of the most relevant topics relating to modern systemic treatments for non-small cell lung cancer (NSCLC). \nThe first session will focus on the gene faults that drive many NSCLCs and on the targeted treatments that exploit these faults\, such as inhibitors of EGFR\, ALK\, ROS1\, B-Raf\, HER2\, MET\, and RET. \nThe second session explores cancer’s relationship with the immune system and focuses on the checkpoint inhibitor group of immunotherapies\, which include PD-1\, PD-L1 and CTLA-4 targeted antibody therapies. \nAudience\nDr Vickers’ goal is to explain the science that underpins each treatment. She also hopes to provide learners with a broad understanding of why treatments work well for some patients but not for others. \nThis half day course is ideal for research nurses\, clinical nurse specialists\, pharmacists and clinical trials coordinators. It may also be of interest to other healthcare professionals involved in the diagnosis and treatment of people with lung cancer\, and to junior doctors. \nACCEND\nNHS England’s ACCEND Programme aims to support the development of a skilled and knowledgeable cancer workforce. \nThis course supports Component 3 of the ACCEND pathway\, the Education Framework. \nSpecifically\, this course’s objectives and learning outcomes meet core cancer knowledge needs at both the ‘Foundation of Cancer Care’ and ‘Fundamentals of Cancer Care’ levels. \nThe course will enhance learners’ understanding of cancer biology\, the mechanism of action of systemic cancer treatments\, and the use of biomarkers to select the best treatments for each patient. \nThe knowledge gained through this course will empower staff to feel confident when communicating with patients and their families\, and with clinical and non-clinical colleagues. \nDetailed description\nSession 1\nPresentation 1 – Lung cancer cell biology and genetics \n\nThe cell of origin of various types of lung cancer\nHow and why lung cancer develops\, and the differences between lung cancers in smokers and non-smokers\nThe faulty genes and proteins that drive adenocarcinomas and squamous cell carcinomas\n\nPresentation 2 – Treatments that target EGFR \n\nThe role of EGFR and signalling pathways in NSCLC\nEGFR gene mutations that create sensitivity to EGFR inhibitors\nEGFR inhibitors: 1st\, 2nd\, and 3rd generation\, and beyond\n\n\nPresentation 3 – More targets and treatments \n\nALK & ROS-1 inhibitors\nTargeting B-Raf\, HER2\, MET\, RET\, NTRK\, K-Ras G12C\nWhat about antibody-drug conjugates?\n\nSession 2\nPresentation 4 – Cancer’s relationship with the immune system \n\nHow cancer’s relationship with the immune system changes over time\nMechanisms of immune evasion by cancer cells\nIntroduction to immunotherapy\nWhen is a targeted therapy or immunotherapy more likely to work?\n\nPresentation 5 – Introduction to immune checkpoint inhibitors \n\nIntroduction to checkpoint proteins on T cells\nMechanism of action of immune checkpoint inhibitors\nCombining checkpoint inhibitors with other treatments\n\nPresentation 6 – How can we predict who will benefit from them? \n\nMeasuring PD-L1 protein levels and tumour mutation burden\nPreparing the patient: antibiotics\, diet\, and other influences on the microbiome\n\nPresentation 7 – Experience from trials \n\nWhat have we learned from clinical trials with PD-1\, PD-L1\, and CTLA-4-targeted antibodies\n\nPre-course preparation\nElaine has created two YouTube playlists about cancer biology and cancer treatments to help learners get the most out of her courses. Each playlist contains 10 videos between 3 and 8 minutes long. \nShe advises “If you’re short on time and you’re not sure about the relationship between DNA\, genes and proteins\, I would suggest watching the Cells\, DNA\, genes and chromosomes and From genes to proteins videos from the Cancer Basics playlist as a priority. Also\, if you’re new to cancer\, I’d recommend the Mutations cause cancer video and\, in order to understand how cancer cells interact with the cells around them\, watch the Tumours are complicated places video.” \n“In the Cancer Treatments playlist\, there are videos about all the various treatments I’ll be mentioning. The two I’d prioritise explain why we use small chemical compounds (small molecules) and antibodies as cancer treatments. If you have more time\, do also watch the videos on kinase inhibitors and immune checkpoint inhibitors.” \nAbout Elaine Vickers\nDr Elaine Vickers\nElaine Vickers of Science Communicated Ltd has a PhD in Molecular Biology. She has worked as a cancer educator for over twenty years. \nShe is passionate about demystifying the science behind cancer biology and the latest cancer treatments such as kinase inhibitors\, monoclonal antibodies\, and immunotherapies. \nElaine is experienced in teaching people with any level of scientific or medical knowledge. She particularly loves teaching nurses and other health professionals who might feel daunted by the idea of learning about cancer science. \nHer book\, A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy\, is now in its second edition. The first edition was Highly Commended by the British Medical Association book awards. \nElaine also makes short educational videos on cancer biology and treatments\, which you can find on her YouTube channel: https://www.youtube.com/@DrElaineVickers \nFinancial information\nIf you are employed by Newcastle Hospitals NHS Foundation Trust\, you can use the coupon code NUTH at the checkout to make a provisional booking and you will need to arrange access to in-house development funding. Your booking will remain provisional until your request has been validated with a funding/study leave reference. \nIf you are not employed by the Newcastle Hospitals an online card payment is required at the point of booking. Alternatively\, if you are to be funded by your employer an invoice can be requested by using the coupon code Invoice. \nIf you are a LET employee you will need to pay by card as we are unable to invoice LETs. \nPlease see Coupons for further information relating to coupon codes and how to use them at checkout. \nCancellation and refunds policy\nShould you no longer be able to attend the event on the booked date\, please contact the Academy as we may be able to offer an alternative date subject to an admin charge. \nShould you still wish to cancel your booking\, you or your employer will be charged as per the fees outlined below.  Please contact nuth.newcastlehospitalsskillsacademy@nhs.net to cancel your booking. \n\n\n\nTimescale\nFee paying course\n\n\nOver 6 weeks\n£25 admin charge\n\n\n2 to 6 weeks\n50% of course fee\n\n\n0 to 2 weeks\n100% of course fee\n\n\n\nIf you do not attend on the day\, you will be charged the full cost of the event place. \nSee our Terms & Conditions and Cancellations & Refunds pages for more details.
URL:https://skillsacademy.newcastle-hospitals.nhs.uk/course/targeted-treatments-and-immunotherapy-for-lung-cancer/
LOCATION:Virtual delivery via MS Teams
CATEGORIES:Cancer courses
ATTACH;FMTTYPE=image/jpeg:https://skillsacademy.newcastle-hospitals.nhs.uk/wp-content/uploads/2024/10/Lung-Cancer-Image.jpg
ORGANIZER;CN="Newcastle Hospitals Skills Academy":MAILTO:nuth.newcastlehospitalsskillsacademy@nhs.net
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