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DTSTART;TZID=Europe/London:20241112T093000
DTEND;TZID=Europe/London:20241112T123000
DTSTAMP:20250429T144450Z
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SUMMARY:Introduction to Precision Cancer Medicine – November 2024
DESCRIPTION:The fundamental idea of precision medicine is to offer each cancer patient a treatment approach that is tailored to the unique biology and genetics of their disease. \nThis two session course provides an understanding of the concepts that underlie precision cancer medicine and both its promise and limitations. \nDr Elaine Vickers – a leading independent educator on the science of new cancer treatments – will explain how far we are able to use precision medicine by exploring the features of cancer we can target now\, and where we might get to in the future\, as well as looking at when precision medicine fails\, and why expectations and realities don’t always align. \nCourse delivery\nThe course comprises two morning sessions delivered online via Microsoft Teams: \nSession One\n\nTuesday 12 November 2024 9:30am – 12:30pm\nAn introduction to the scientific concepts that underpin the concept of precision medicine looking at the features of cancer cells that we can target\, the treatments available\, and the tests and technologies needed to match targets with treatments. Includes the example of non-squamous\, non-small cell lung cancer\, where a precision approach is often already used. \nSession Two \nTuesday 19 November 2024 9:30am – 12:30pm\nThe session focuses on the limitations and current realities of precision medicine. Elaine describes why a precision approach isn’t always possible\, or might not give the best outcome\, for every patient. \nThe session closes by exploring progress made in offering a precision-approach with three of the most common cancers: breast\, bowel\, and prostate\, and considering where we go from here. \nDelegates will be given access to recordings of all sessions for three months after completion of the course. If you are unable to attend a session the recording will ensure you can review any content you have missed. \nLearning outcomes\nBy the end of this introduction to precision cancer medicine delegates will: \n\nUnderstand what precision medicine means – the treatments we are currently working with\, what we can and can’t target and how immunotherapy fits in\nExplore the treatments we use in precision medicine – antibody-based treatments; small molecule kinase inhibitors; and immunotherapies\nRecognise testing methods and potential treatment targets – what we can test for and where to look\, testing for mutations and presence of proteins\, identifying patterns of mutations and what commercial testing platforms can tell us\nAppreciate whether or not we understand how to make a good match and why not everyone benefits from a precision-based approach\nGrasp some of the unsolved questions and limitations in precision medicine\nBe able to reflect on where we have got to\, and where we are heading\, with precision cancer medicine for lung\, breast\, bowel and prostate cancer.\n\nCourse lead\nDr Elaine Vickers PhD of Science Communicated Ltd\nDr Elaine Vickers\, PhD of Science Communicated Ltd has worked as a cancer educator for over twenty years and has previously acted as science communicator for three of the UK’s leading medical research charities\, including four years in the Science Information team at Cancer Research UK. \nElaine is passionate about demystifying the science behind cancer biology and the latest cancer treatments such as kinase inhibitors\, monoclonal antibodies and immunotherapies. \nShe is experienced in teaching people with any level of scientific or medical knowledge from cancer patients through to medical oncologists translating complex and often overwhelming topics into easily digestible and understandable knowledge\, using colourful illustrations to explain scientific concepts. \nHer book\, A Beginner’s Guide to Targeted Cancer Treatments\, was commended by the British Medical Association book awards. A second edition is due out in 2024. \nAudience\nThis content is ideal for research nurses\, clinical nurse specialists\, pharmacists\, and clinical trials coordinators. It may also be of interest to other healthcare professionals involved in the diagnosis and treatment of people with cancer\, including junior doctors. \nBooking\nTo book a place on this course go to Tickets at the bottom of the page. \nAt checkout you can make an online card payment or enter a coupon code to make alternative payment arrangements. \nAlternative payment arrangements include: \n\nrequesting an invoice (INVOICE)\,\nThe Newcastle upon Tyne Hospitals NHS Foundation Trust staff internal funding (NUTH) – you will need to complete a Trust study leave form.\n\nPlease see the Making payments & Coupons sections of the Help and FAQs.
URL:https://skillsacademy.newcastle-hospitals.nhs.uk/course/introduction-to-precision-cancer-medicine-november-2024/
LOCATION:Virtual delivery via MS Teams
ATTACH;FMTTYPE=image/jpeg:https://skillsacademy.newcastle-hospitals.nhs.uk/wp-content/uploads/2023/10/MicrosoftTeams-image-1.jpg
ORGANIZER;CN="Newcastle Hospitals Skills Academy":MAILTO:nuth.newcastlehospitalsskillsacademy@nhs.net
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DTSTART;TZID=Europe/London:20241127T093000
DTEND;TZID=Europe/London:20241127T123000
DTSTAMP:20250429T143940Z
CREATED:20241001T075411Z
LAST-MODIFIED:20250429T143940Z
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SUMMARY:Novel Immunotherapies for Solid Tumours - November 2024
DESCRIPTION:An introduction to progress made in developing novel immunotherapies for solid tumours (excluding immune checkpoint inhibitors). \nOverview\nThis course emphasises the progress made in developing novel immunotherapies for solid tumours\, such as CAR T cell therapy\, TCR-engineered T cell therapy\, tumour infiltrating lymphocytes\, T cell engagers\, and vaccine-based treatments. \nOver the course of one morning\, Dr Elaine Vickers – a leading independent educator on the science of new cancer treatments – discusses novel approaches that may have a future as standard treatments for solid tumours including features of solid tumours that provoke the immune system and those that allow cancer cells to survive and thrive. \nElaine will describe cancers where novel immunotherapies are being most intensively explored\, such as in the treatment of: \n\ncancers already known to be sensitive to immunotherapy\, such as melanoma skin cancer\ncancers where new treatments are desperately needed\, such as pancreatic cancer and glioblastoma\ncancers where a particularly promising target has been identified\, such as Claudin 18.2 in stomach cancer and other GI cancers.\n\nIn the second session of the morning\, Elaine focuses on cell-based immunotherapies such as TIL (tumour infiltrating lymphocyte) therapy\, CAR T cell therapy\, and TCR-engineered T cell therapy. She explains why we haven’t made more progress with these treatments and explores how this might change in the future. \nIn the final session\, Elaine will examine some of the most innovative and exciting immunotherapies being developed\, including T cell engagers and mRNA vaccines. \nAudience\nThis content is ideal for research nurses\, clinical nurse specialists\, pharmacists\, and clinical trials coordinators. It may also interest other healthcare professionals wanting to improve their understanding of immunotherapy. \nAttendance on Elaine’s other course: A Beginner’s Guide to Cancer Immunotherapy would be ideal preparation for this course. \nAs ever\, Elaine will use colourful illustrations and jargon-free explanations to help learners gain a broad understanding of the concepts covered. \nCourse delivery\nThe course delivery date is Wednesday 27th November 2024 and is to be delivered online via Microsoft Teams as follows: \n9.30am – Introduction to novel immunotherapies for solid tumours \n\nThe cancer-immunity cycle\nWhy not every cancer is sensitive to immunotherapy; exploring ‘Hot’\, ‘Cold’\, ‘Immune-suppressed’ and ‘Immune-excluded’ cancers\nHow cancer’s relationship with the immune system differs in different cancer types and the mechanisms that drive this\nIntroducing the cancers in which novel immunotherapies are being explored\n\nQ&A/break \n10.30am – Progress in cell-based immunotherapy for solid tumours \n\nWhere it started: TIL (tumour infiltrating lymphocyte) therapy\nIntroduction to CAR T cell therapy\nCAR proteins and their targets\nWhy don’t we have CAR T cell therapies for solid tumours?\nAn alternative approach: TCR-engineered T cells\n\nQ&A/break \n11.30am – Treatment vaccines\, T cell engagers and other novel approaches in trials \n\nVaccine-based immunotherapy – the general idea and the multitude of approaches being investigated\nPromising results from mRNA vaccine trials\nTebentafusp and tarlatamab – the first T cell engagers approved for solid tumours\nImmunotherapies that leverage macrophages and NK cells\n\nQ&A \n12.30pm – close \nCourse lead\nDr Elaine Vickers PhD of Science Communicated Ltd\nDr Elaine Vickers\, PhD of Science Communicated Ltd has worked as a cancer educator for over twenty years and has previously acted as science communicator for three of the UK’s leading medical research charities\, including four years in the Science Information team at Cancer Research UK. \nElaine is passionate about demystifying the science behind cancer biology and the latest cancer treatments such as kinase inhibitors\, monoclonal antibodies and immunotherapies. \nShe is experienced in teaching people with any level of scientific or medical knowledge from cancer patients through to medical oncologists translating complex and often overwhelming topics into easily digestible and understandable knowledge\, using colourful illustrations to explain scientific concepts. \nThe second edition of her book\, A Beginner’s Guide to Targeted Cancer Treatments – commended by the British Medical Association book awards – is due out by the end of 2024. \nBooking\nTo book a place on this course go to Tickets at the bottom of the page. \nAt checkout you can make an online card payment or enter a coupon code to make alternative payment arrangements. \nAlternative payment arrangements include: \n\nrequesting an invoice (INVOICE)\,\nThe Newcastle upon Tyne Hospitals NHS Foundation Trust staff internal funding (NUTH) – you will need to complete a Trust study leave form.\n\nPlease see the Making payments & Coupons sections of the Help and FAQs.
URL:https://skillsacademy.newcastle-hospitals.nhs.uk/course/novel-immunotherapies-for-solid-tumours-november-2024-2/
LOCATION:Virtual delivery via MS Teams
ATTACH;FMTTYPE=image/jpeg:https://skillsacademy.newcastle-hospitals.nhs.uk/wp-content/uploads/2023/10/MicrosoftTeams-image.jpg
ORGANIZER;CN="Newcastle Hospitals Skills Academy":MAILTO:nuth.newcastlehospitalsskillsacademy@nhs.net
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