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DTSTART;TZID=Europe/London:20260707T133000
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DTSTAMP:20260404T150726
CREATED:20250922T152704Z
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UID:10000130-1783431000-1784046600@skillsacademy.newcastle-hospitals.nhs.uk
SUMMARY:Demystifying the Science Behind Systemic Treatments for Prostate\, Bladder and Kidney Cancers - July 2026
DESCRIPTION:Delivered over two afternoon sessions\, Dr Elaine Vickers – a leading independent educator on the science of new cancer treatments – will provide an introduction to the science behind a wide variety of systemic treatments given to people with prostate\, bladder\, or kidney cancer. \nSession 1: The first half-day session is dedicated to prostate cancer. Hormone therapies are central to the treatment of prostate cancer\, Elaine will describe their mechanism of action\, explain why cancers become resistant to them\, and look at the new generation of hormone therapies in development. She will also describe PSMA-targeted treatment approaches\, PARP inhibitors\, and PI3K- and AKT-targeted treatments. \nSession 2: The second half-day session is about bladder and kidney cancer. Much of the session will be focused on immune checkpoint inhibitors and their uses and limitations. Elaine will also describe angiogenesis inhibitors and targeted therapies such as antibody-drug conjugates and FGFR inhibitors. \nAs ever\, Elaine’s presentations will be full of colourful diagrams\, and she will explain the science behind the treatments using clear\, understandable descriptions. She will explore how the treatments are designed to work\, but also explain why they often only work for a time\, before the person’s disease becomes resistant. \nAudience\nDr Vickers’ goal is to explain the science that underpins each treatment. She also hopes to provide learners with a broad understanding of why treatments work well for some patients but not for others. \nThis half day course is ideal for research nurses\, clinical nurse specialists\, pharmacists and clinical trials coordinators. It may also be of interest to other healthcare professionals involved in the diagnosis and treatment of people with prostate\, bladder and kidney cancers. \nACCEND\nNHS England’s ACCEND Programme aims to support the development of a skilled and knowledgeable cancer workforce. \nThis course supports Component 3 of the ACCEND pathway\, the Education Framework. \nSpecifically\, this course’s objectives and learning outcomes meet core cancer knowledge needs at both the ‘Foundation of Cancer Care’ and ‘Fundamentals of Cancer Care’ levels. \nThe course will enhance learners’ understanding of cancer biology\, the mechanism of action of systemic cancer treatments\, and the use of biomarkers to select the best treatments for each patient. \nThe knowledge gained through this course will empower staff to feel confident when communicating with patients and their families\, and with clinical and non-clinical colleagues. \nDetailed description\nSession 1\nPresentation 1 – An introduction to the biology and genetics of prostate cancer \n\nRisk factors for prostate cancer\nCommon gene mutations and their consequences\nPatterns and numbers of mutations in prostate cancer cells\n\nPresentation 2 – Hormone therapy for prostate cancer \n\nThe importance of androgen receptors in driving the development and spread of prostate cancer\nAndrogen-deprivation therapy (LHRH agonists/antagonists; anti-androgens)\nSecond-generation hormone therapies and beyond\nOvercoming resistance to current hormone therapies\n\nPresentation 3 – Targeted treatments for prostate cancer \n\nThe logic behind targeted radioligands\nLutetium-177 (177Lu-PSMA-617) and other ways of targeting PSMA\nPARP inhibitors for prostate cancers with defects in homologous recombination\nPI3K & AKT inhibitors\n\nSession 2\nPresentation 4 – Biology and genetics of kidney and bladder cancer \n\nRisk factors\nCommon mutations\n\nImmunotherapy for kidney & bladder cancer – part 1 \n\nHow the immune system recognises and reacts to the presence of cancer\nThe importance of the immune microenvironment\n\nPresentation 5 – Immunotherapy for kidney & bladder cancer – part 2 \n\nIntroduction to immunotherapy\nWhy immunotherapy sometimes works and sometimes doesn’t\nMechanism of action of immune checkpoint inhibitors\nCheckpoint inhibitor therapy for kidney\, bladder and prostate cancer\n\nPresentation 6 – Targeted treatments for kidney cancer and bladder cancer \n\nWhy angiogenesis inhibitors are effective treatments for kidney cancer\nVEGF\, mTOR\, and HIF targeted angiogenesis inhibitors (e.g. pazopanib\, axitinib\, cabozantinib\, lenvatinib\, everolimus\, belzutifan)\nBladder cancer treatments that target FGF receptors (erdafitinib\, pemigatinib)\nAntibody-drug conjugates for bladder cancer (enfortumab vedotin)\n\nPre-course preparation\nElaine has created two YouTube playlists about cancer biology and cancer treatments to help learners get the most out of her courses. Each playlist contains 10 videos between 3 and 8 minutes long. \nElaine advises “If you’re short on time and you’re not sure about the relationship between DNA\, genes and proteins\, I would suggest watching the Cells\, DNA\, genes and chromosomes and From genes to proteins videos from the Cancer Basics playlist as a priority. Also\, if you’re new to cancer\, I’d recommend the Mutations cause cancer video and\, in order to understand how cancer cells interact with the cells around them\, watch the Tumours are complicated places video.” \n“In the Cancer Treatments playlist\, there are videos about all the various treatments I’ll be mentioning. The two I’d prioritise explain why we use small chemical compounds (small molecules) and antibodies as cancer treatments. If you have more time\, do also watch the videos on kinase inhibitors and immune checkpoint inhibitors.” \nAbout Elaine Vickers\nDr Elaine Vickers\nElaine Vickers of Science Communicated Ltd has a PhD in Molecular Biology. She has worked as a cancer educator for over twenty years. \nShe is passionate about demystifying the science behind cancer biology and the latest cancer treatments such as kinase inhibitors\, monoclonal antibodies\, and immunotherapies. \nElaine is experienced in teaching people with any level of scientific or medical knowledge. She particularly loves teaching nurses and other health professionals who might feel daunted by the idea of learning about cancer science. \nHer book\, A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy\, is now in its second edition. The first edition was Highly Commended by the British Medical Association book awards. \nElaine also makes short educational videos on cancer biology and treatments\, which you can find on her YouTube channel: https://www.youtube.com/@DrElaineVickers \nFinancial information\nIf you are employed by Newcastle Hospitals NHS Foundation Trust\, you can use the coupon code NUTH at the checkout to make a provisional booking and you will need to arrange access to in-house development funding. Your booking will remain provisional until your request has been validated with a funding/study leave reference. \nIf you are not employed by the Newcastle Hospitals an online card payment is required at the point of booking. Alternatively\, if you are to be funded by your employer an invoice can be requested by using the coupon code Invoice. \nIf you are a LET employee you will need to pay by card as we are unable to invoice LETs. \nPlease see Coupons for further information relating to coupon codes and how to use them at checkout. \nCancellation and refunds policy\nShould you no longer be able to attend the event on the booked date\, please contact the Academy as we may be able to offer an alternative date subject to an admin charge. \nShould you still wish to cancel your booking\, you or your employer will be charged as per the fees outlined below.  Please contact nuth.newcastlehospitalsskillsacademy@nhs.net to cancel your booking. \n\n\n\nTimescale\nFee paying course\n\n\nOver 6 weeks\n£25 admin charge\n\n\n2 to 6 weeks\n50% of course fee\n\n\n0 to 2 weeks\n100% of course fee\n\n\n\nIf you do not attend on the day\, you will be charged the full cost of the event place. \nSee our Terms & Conditions and Cancellations & Refunds pages for more details.
URL:https://skillsacademy.newcastle-hospitals.nhs.uk/course/targeted-treatments-and-immunotherapy-for-urological-cancers/
LOCATION:Virtual delivery via MS Teams
CATEGORIES:Cancer courses
ATTACH;FMTTYPE=image/jpeg:https://skillsacademy.newcastle-hospitals.nhs.uk/wp-content/uploads/2025/09/Kidney-Cancer.jpg
ORGANIZER;CN="Newcastle Hospitals Skills Academy":MAILTO:nuth.newcastlehospitalsskillsacademy@nhs.net
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