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DTSTART;TZID=Europe/London:20261110T133000
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DTSTAMP:20260922T151652Z
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UID:10000131-1794317400-1794328200@skillsacademy.newcastle-hospitals.nhs.uk
SUMMARY:Targeted treatments and immunotherapy for Haematological Cancers - November 2026
DESCRIPTION:Delivered over two afternoon sessions\, Dr Elaine Vickers – a leading independent educator on the science of new cancer treatments – will guide you through many of the most relevant topics relating to modern systemic treatments for haematological cancers. \nSession 1: The first session will focus on how haematological cancers develop and the faulty cells that cause them. Elaine will also describe the unique features of B cells and explain why they give rise to over 80% of haematological cancers diagnosed in the UK. Elaine also explains the mechanisms of action of various treatments given to people with B cell cancers: chronic lymphocytic leukaemia\, acute lymphoblastic leukaemia\, and non-Hodgkin lymphoma. \nSession 2: In the second session\, Elaine explores treatments for multiple myeloma\, acute myeloid leukaemia\, Hodgkin lymphoma\, and chronic myeloid leukaemia. She also explains the science behind CAR T cell therapy and describes the progress made to date and innovations for the future. \nAudience\nDr Vickers’ goal is to explain the science that underpins each treatment. She also hopes to provide learners with a broad understanding of why treatments work well for some patients but not for others. \nThis half day course is ideal for research nurses\, clinical nurse specialists\, pharmacists and clinical trials coordinators. It may also be of interest to other healthcare professionals involved in the diagnosis and treatment of people with haematological cancers\, and to junior doctors. \nACCEND\nNHS England’s ACCEND Programme aims to support the development of a skilled and knowledgeable cancer workforce. \nThis course supports Component 3 of the ACCEND pathway\, the Education Framework. \nSpecifically\, this course’s objectives and learning outcomes meet core cancer knowledge needs at both the ‘Foundation of Cancer Care’ and ‘Fundamentals of Cancer Care’ levels. \nThe course will enhance learners’ understanding of cancer biology\, the mechanism of action of systemic cancer treatments\, and the use of biomarkers to select the best treatments for each patient. \nThe knowledge gained through this course will empower staff to feel confident when communicating with patients and their families\, and with clinical and non-clinical colleagues. \nDetailed description\nSession 1 Tuesday 10 November 2026 1:30pm – 4:30pm\nPresentation 1 – Biology and genetics of haematological cancers \n\nCell of origin of different haematological cancers\nTypes of DNA damage in haematological cancers\nConsequences of common chromosome translocations and other mutations\nUnderstanding the incidence of blood cancers in infants and children\n\nPresentation 2 – Features of B cell cancers & an overview of treatment approaches \n\nWhy most haematological cancers are derived from B cells\nImportant features of B cell cancers\, e.g. indolent vs. aggressive\, the effect of TP53 mutations\, the importance of B cell receptor signalling\nAntibody-based treatments: naked antibodies\, conjugated antibodies\, BiTEs & bi-specifics\nSmall molecules with kinase and non-kinase targets\nCell-based therapies\n\nPresentation 3 – Treatments for B cell cancers: chronic lymphocytic leukaemia\, non-Hodgkin lymphoma and acute lymphoblastic leukaemia \n\nCD20-targeted antibody therapies (e.g. rituximab\, obinutuzumab)\nB cell receptor signalling pathway inhibitors targeting BTK\, PI3Kδ & CD79B (e.g. ibrutinib\, acalabrutinib\, idelalisib\, polatuzumab vedotin)\nBcl-2 inhibitors (e.g. venetoclax)\nBi-specific antibodies that act as T cell engagers (e.g. blinatumomab\, glofitamab\, mosunetuzumab\, epcoritamab\, odronextamab)\n\nSession 2 – Tuesday 24 November 1:30pm – 4:30pm\nPresentation 4 – Treatments for myeloma \n\nProteasome inhibitors (e.g. bortezomib)\nImmunomodulators (e.g. thalidomide\, pomalidomide) and novel cereblon modulators (e.g. iberdomide\, mezigdomide)\nMonoclonal antibodies targeting CD38 (e.g. daratumumab\, isatuximab)\nT cell engagers targeting BCMA and GPRC5D (e.g. talquetemab\, teclistamab\, elranatamab)\nAntibody-drug conjugates (e.g. balantamab mafodotin)\n\nPresentation 5 – Treatments for acute myeloid leukaemia\, Hodgkin lymphoma\, and chronic myeloid leukaemia \n\nTreatments for acute myeloid leukaemia: an overview of targets and focus on FLT3 inhibitors\nBcr-Abl inhibitors for chronic myeloid leukaemia (e.g. imatinib\, dasatinib\, nilotinib\, ponatinib\, asciminib)\nImmune checkpoint inhibitors for Hodgkin lymphoma (e.g. pembrolizumab\, nivolumab)\n\nPresentation 6 –  CAR T cell therapy for haematological cancers \n\nOverview of the CAR T cell process\nCAR protein design – what each bit does and why it matters\nCAR protein targets\nReasons for side effects of CAR T cells\nReasons for resistance and relapse\nOverview of the results so far\, the lessons learned\, and what the future might look like\n\nPre-course preparation\nElaine has created two YouTube playlists about cancer biology and cancer treatments to help learners get the most out of her courses. Each playlist contains 10 videos between 3 and 8 minutes long. \nElaine advises “If you’re short on time and you’re not sure about the relationship between DNA\, genes and proteins\, I would suggest watching the Cells\, DNA\, genes and chromosomes and From genes to proteins videos from the Cancer Basics playlist as a priority. Also\, if you’re new to cancer\, I’d recommend the Mutations cause cancer video and\, in order to understand how cancer cells interact with the cells around them\, watch the Tumours are complicated places video.” \n“In the Cancer Treatments playlist\, there are videos about all the various treatments I’ll be mentioning. The two I’d prioritise explain why we use small chemical compounds (small molecules) and antibodies as cancer treatments. If you have more time\, do also watch the videos on kinase inhibitors and immune checkpoint inhibitors.” \nAbout Elaine Vickers\nDr Elaine Vickers\nElaine Vickers of Science Communicated Ltd has a PhD in Molecular Biology. She has worked as a cancer educator for over twenty years. \nShe is passionate about demystifying the science behind cancer biology and the latest cancer treatments such as kinase inhibitors\, monoclonal antibodies\, and immunotherapies. \nElaine is experienced in teaching people with any level of scientific or medical knowledge. She particularly loves teaching nurses and other health professionals who might feel daunted by the idea of learning about cancer science. \nHer book\, A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy\, is now in its second edition. The first edition was Highly Commended by the British Medical Association book awards. \nElaine also makes short educational videos on cancer biology and treatments\, which you can find on her YouTube channel: https://www.youtube.com/@DrElaineVickers \nFinancial information\nIf you are employed by Newcastle Hospitals NHS Foundation Trust\, you can use the coupon code NUTH at the checkout to make a provisional booking and you will need to arrange access to in-house development funding. Your booking will remain provisional until your request has been validated with a funding/study leave reference. \nIf you are not employed by the Newcastle Hospitals an online card payment is required at the point of booking. Alternatively\, if you are to be funded by your employer an invoice can be requested by using the coupon code Invoice. \nIf you are a LET employee you will need to pay by card as we are unable to invoice LETs. \nPlease see Coupons for further information relating to coupon codes and how to use them at checkout. \nCancellation and refunds policy\nShould you no longer be able to attend the event on the booked date\, please contact the Academy as we may be able to offer an alternative date subject to an admin charge. \nShould you still wish to cancel your booking\, you or your employer will be charged as per the fees outlined below.  Please contact nuth.newcastlehospitalsskillsacademy@nhs.net to cancel your booking. \n\n\n\nTimescale\nFee paying course\n\n\nOver 6 weeks\n£25 admin charge\n\n\n2 to 6 weeks\n50% of course fee\n\n\n0 to 2 weeks\n100% of course fee\n\n\n\nIf you do not attend on the day\, you will be charged the full cost of the event place. \nSee our Terms & Conditions and Cancellations & Refunds pages for more details.
URL:https://skillsacademy.newcastle-hospitals.nhs.uk/course/targeted-treatments-and-immunotherapy-for-haematological-cancers/
LOCATION:Virtual delivery via MS Teams
CATEGORIES:Cancer courses
ATTACH;FMTTYPE=image/jpeg:https://skillsacademy.newcastle-hospitals.nhs.uk/wp-content/uploads/2024/09/Haematology-banner-scaled.jpg
ORGANIZER;CN="Newcastle Hospitals Skills Academy":MAILTO:nuth.newcastlehospitalsskillsacademy@nhs.net
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DTSTART;TZID=Europe/London:20270114T093000
DTEND;TZID=Europe/London:20270114T123000
DTSTAMP:20260908T130612Z
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LAST-MODIFIED:20260908T130612Z
UID:10000172-1799919000-1799929800@skillsacademy.newcastle-hospitals.nhs.uk
SUMMARY:The 4Ps Researcher Development Programme (January - May 2027) Cohort 13
DESCRIPTION:The 4Ps Programme was developed by research experts in Newcastle\, designed to support healthcare professionals’ needs no matter where they are on the “research interested” to “Aspiring Clinical Academic” continuum. This welcoming jargon-free modular programme has four modules: \n\nPlace\nProject\nPerson\nPlan\n\nThey provide delegates with the skills\, knowledge and confidence to move forward with research. The starting point for the programme is our pre-requisite Foundation session. \nThe programme is delivered by a range of clinical-academic colleagues\, and with input from relevant organisations including the Research Design Service\, Patient and Public Involvement panels\, universities and funders. \nAttendance\nCohort 13 of the 4Ps Researcher Development Programme consists of the following sessions: \n\n\n\nSession\nDay\nDate\nTime\n\n\nFoundation\nThursday\n14 January 2027\n9:30am – 12:30pm\n\n\nPlace\nTuesday\n9 February 2027\n1:00pm – 4:00pm\n\n\nProject\nWednesday\n10 March 2027\n1:00pm – 4:00pm\n\n\nPerson\nThursday\n22 April 2027\n9:30am – 12:30pm\n\n\nPlan\nTuesday\n11 May 2027\n1:00pm – 4:00pm\n\n\n\nThese sessions will be delivered via MS Teams. \nBooking\nTo book a place on this course go to Tickets at the bottom of the page. At the checkout you can make an online card payment or enter a coupon code to make alternative payment arrangements. \nAlternative payment arrangements include: \n\nrequesting an invoice (INVOICE)\,\nNewcastle upon Tyne Hospitals NHS Foundation Trust staff internal funding (NUTH).\n\nPlease see the Making payments & Coupons sections of the Help and FAQs. \nWhat are the 4Ps?\n\nPlace\n“I am as nowhere as I can be\, can you add some somewhere to me?” \nThis module will help you to think about developing the right collaborations\, identifying the right expertise and choosing and engaging with mentors and supervisors who can support you on your journey. This is such an important ingredient as relationships with mentors and supervisors can influence your whole career and can really help you to go places. \n  \n\nProject\n“Push harder than yesterday if you want a different tomorrow…” \nThis module will explore a recipe of key ingredients for a research project such as: \n\nlinking your work to strategic priorities\nlooking at the literature\ndeveloping your research question\nidentifying the right methodology and\nultimately starting to develop a project plan or application for funding.\n\n\nPerson\n\n“The best project you will ever work on is you…” \nThis module will help you to focus on you as an individual\, as a researcher and as a leader. We’ll cover things like developing your research CV\, writing activities\, public speaking and all things confidence building for you as a researcher. \n  \n\nPlan\n“It takes as much energy to wish as it does to plan.” \nPlanning is so important for any piece of research\, but it’s not just about planning the project. This session will help you to think about the bigger picture\, influencing up\, down and across. Also what to do next regardless of the outcome of a research related funding or fellowship application. \nGetting started\nThe starting point for the course is the Foundation session – an essential building block which equips colleagues to go on to the subsequent modules. \nWe learn about the research landscape and begin to think about where we fit into it. We cover topics like the difference between research\, audit and service evaluation. \nWe spend time thinking about who we are as clinicians\, as potential researchers\, and what the opportunities might be for us. \nIntended Audience\nThe Newcastle Hospitals’ 4Ps Programme supports the needs of all registered healthcare professionals regardless of where they are on their research journey. \nCancellation and refunds policy\nShould you no longer be able to attend the event on the booked date\, please contact the Academy as we may be able to offer an alternative date subject to an admin charge.  To cancel your place you must email nuth.newcastlehospitalsskillsacademy@nhs.net \nShould you still wish to cancel your booking\, you or your employer will be charged as per the fees outlined below. \n\n\n\nTimescale\nFee paying course\n\n\nOver 6 weeks\n£25 admin charge\n\n\n2 to 6 weeks\n50% of course fee\n\n\n0 to 2 weeks\n100% of course fee\n\n\n\nIf you do not attend on the day\, you will be charged the full cost of the event place. \nSee our Terms & Conditions and Cancellations & Refunds pages for more details.
URL:https://skillsacademy.newcastle-hospitals.nhs.uk/course/the-4ps-researcher-development-programme-january-may-2027-cohort-13/
LOCATION:Virtual delivery via MS Teams
CATEGORIES:The 4 Ps Researcher Development Programme
ATTACH;FMTTYPE=image/jpeg:https://skillsacademy.newcastle-hospitals.nhs.uk/wp-content/uploads/2023/09/MakeSpace4ResearchPurple-red.jpg
ORGANIZER;CN="Newcastle Hospitals Skills Academy":MAILTO:nuth.newcastlehospitalsskillsacademy@nhs.net
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